Vitiligo is a common limit of Office acquired or generalized depigmentation
of the skin disease. Body parts can occur, common in the dorsal, wrist, forearm,
face, neck and around the genitals and the like. Female genital also occur,
mostly young women.
The symptoms of vitiligo
No significant gender differences in each age group may be the disease, but the adolescent predilection. Lesions depigmentation spots, often white, but also as a pale pink, smooth surface without rash. White state clearly that the edge than normal skin pigmentation, normal or white inside white hair. Lesions occur in damage by sunlight and friction parts, more symmetrical distribution of lesions. Leukoplakia also often distributed by segmental nerve zonal arrangement. In addition to the damage to the skin, the lips, the labia, the glans and inside the foreskin mucosa are frequently involved.
The disease without symptoms, a small number of patients simultaneously or before the onset of the lesion itching. Vitiligo is often accompanied by other autoimmune diseases, such as diabetes, thyroid disease, adrenal insufficiency, scleroderma, atopic dermatitis, alopecia areata. Specific sub-type as follows:
1. localized
(1) focal type one or multiple white spots confined to one area, but not to show the distribution segment;
(2) single-sided (segmental) at one or more white spots showed segmental distribution in the midline suddenly disappeared;
(3) type involving only the mucosa mucosa.
2. scattered type
(1) an unusual type widely scattered white and distribution;
(2) face acral distribution in the face and limbs;
(3) mixed segmental facial extremities type and / or unusual hybrid distribution.
3. Pan hairstyle
All or almost all of depigmentation. Vitiligo is more than 90% of sporadic type, the rest of the vitiligo pan-hair more than localized.
According Lesions depigmentation situation can be completely disease is divided into two kinds of type and incomplete. The former dihydroxy phenylalanine (DOPA) reaction negative melanocytes disappear, poor response to treatment. The latter reaction of DOPA positive melanocytes disappear not only reduce the number of large chance of cure.
The symptoms of vitiligo
No significant gender differences in each age group may be the disease, but the adolescent predilection. Lesions depigmentation spots, often white, but also as a pale pink, smooth surface without rash. White state clearly that the edge than normal skin pigmentation, normal or white inside white hair. Lesions occur in damage by sunlight and friction parts, more symmetrical distribution of lesions. Leukoplakia also often distributed by segmental nerve zonal arrangement. In addition to the damage to the skin, the lips, the labia, the glans and inside the foreskin mucosa are frequently involved.
The disease without symptoms, a small number of patients simultaneously or before the onset of the lesion itching. Vitiligo is often accompanied by other autoimmune diseases, such as diabetes, thyroid disease, adrenal insufficiency, scleroderma, atopic dermatitis, alopecia areata. Specific sub-type as follows:
1. localized
(1) focal type one or multiple white spots confined to one area, but not to show the distribution segment;
(2) single-sided (segmental) at one or more white spots showed segmental distribution in the midline suddenly disappeared;
(3) type involving only the mucosa mucosa.
2. scattered type
(1) an unusual type widely scattered white and distribution;
(2) face acral distribution in the face and limbs;
(3) mixed segmental facial extremities type and / or unusual hybrid distribution.
3. Pan hairstyle
All or almost all of depigmentation. Vitiligo is more than 90% of sporadic type, the rest of the vitiligo pan-hair more than localized.
According Lesions depigmentation situation can be completely disease is divided into two kinds of type and incomplete. The former dihydroxy phenylalanine (DOPA) reaction negative melanocytes disappear, poor response to treatment. The latter reaction of DOPA positive melanocytes disappear not only reduce the number of large chance of cure.
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